Hyperprolactinemic Galactorrhea Following Pneumonectomy for Tuberculosis Sequelae
Keywords:
hyperprolactinemia; pneumonectomy; galactorrhea; tuberculosis.Abstract
Introduction: Hyperprolactinemia is a neuroendocrine disorder characterized by elevated serum prolactin levels, with physiological, pharmacological, or pathological etiologies. Its manifestations include galactorrhea, sexual dysfunction, and infertility.
Objective: To describe a case of hyperprolactinemia secondary to chest trauma in a patient with a history of pneumonectomy due to pulmonary tuberculosis sequelae.
Clinical case report: A 33-year-old woman with a history of pneumonectomy for pulmonary tuberculosis developed galactorrhea and hyperprolactinemia, with normal thyroid and renal function. Pituitary MRI showed no structural lesions or tumors. After ruling out common causes, a diagnosis of hyperprolactinemia secondary to chest trauma was established. Its pathophysiology was attributed to abnormal stimulation of the intercostal and upper thoracic nerves.
Conclusions: This case highlights the importance of considering a history of chest trauma in patients with hyperprolactinemia of no apparent cause, as well as the need for an interdisciplinary clinical approach for its proper diagnosis and management.
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Copyright (c) 2026 Patricia Segura Núñez, Fernando Monge Espinoza, Mayra Orihuela Baldeón, Carlos Eduardo Piscoche Rodríguez, Franco Sebastian Paucar Baldeón, Nidia Bethzabé Riveros-Mendoza , Mariela Vargas
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