Teniosis in Cuba: Epidemiological and molecular evidence of the circulation of Taenia saginata
Keywords:
Teniosis, cysticercosis, epidemiology, molecular diagnosis, CubaAbstract
Introduction: The study of the epidemiology of taeniosis is important for human and veterinary health and prevention and control programs, especially for Taenia solium, which causes human cysticercosis.
Objectives: Provide an overview of the main results related to the epidemiology and diagnosis of taeniosis/cysticercosis in Cuban patients.
Methods: A compilation of three studies was carried out: (i) a cohort of 158 epileptic patients who were studied using Western blot and ELISA techniques; (ii) frequency of infection by intestinal tapeworms in stool samples and adult parasites sent to the IPK between 2010 and 2018; and (iii) molecular identification of 37 samples positive for Taenia sp. using the real-time PCR technique and sequencing of the products obtained.
Results: Antibodies against T. solium and circulating cysticercus antigens were not detected in 100% of the patients studied, suggesting the non-association of neurocysticerosis and epilepsy. It was found that intestinal infection by Taenia spp. it had a prevalence of 0.17% and was the most prevalent cestodiasis in the adult population. It was evidenced that all the molecularly identified samples corresponded to T. saginata, and the sequences of three of the samples, based on the cox 1 gene, confirmed a great homology with isolates from other countries.
Conclusion: These results are useful for an integrated control and better understanding of the dynamics of this zoonosis through the One Health concept and provide experimental evidence about the predominant circulation of T. saginata.
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